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Lab Times Issue 3/2011

Beyond all the wiring that stitches the brain together are the command centers operating from within each neuron, which endow the organ with an exceptional intellectual propensity. Recent research has identified some ‘new’ performers, the regulators of the epigenome. A rendezvous with Annette Schenck and colleagues tells us more.

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Lab Times Issue 1/2011

Only recently, an immunomodulatory role for the ‘cylindromatosis’ tumour suppressor gene (Cyld) has been ascribed. In their pioneering work, George Mosialos and his group have cracked the mechanism of Cyld-dependent regulation of T-cell development with their in vivo mouse model. Excerpts from a tête-à-tête with Mosialos follow...

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Lab Times Issue 5/2010

The need for novel antibiotic formulations with broad spectra has led to a burgeoning focus on bacterial cell biology. As Leendert Hamoen’s team at the University of Newcastle uncovers a potent cellular feature that modulates localisation of membrane proteins in bacteria, does their research offer attractive prompts to the pharma industry?

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Lab Times Issue 4/2010

The human cortex confers man with the exceptional quality of cognizance. While research staggered for years in identifying the ‘cell-intrinsic’ molecular basis of cognition, Marta Nieto and colleagues have been pioneers in illustrating a novel mechanism in cortical development. And that adds another piece to the puzzle...

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